
There’s nothing quite like coming home after a long day of work to the mouthwatering aroma of a warm, home-cooked meal waiting for you. That’s the beauty of this slow cooker beef enchilada casserole—it does all the heavy lifting while you’re out conquering the day. The layers of tender beef, tangy red enchilada sauce, and melty cheese come together effortlessly, so when you walk through the door, dinner feels like a comforting hug. It’s the kind of meal that makes the stress of the day melt away with every bite.
Why You’ll Love This Recipe
This slow cooker beef enchilada casserole combines the rich, bold flavors of Mexican food with the ease of a one-pot dish. It’s perfect for busy weeknights or laid-back weekends. Layers of soft corn tortillas soak up the savory enchilada sauce, while tender beef and melty cheese create a combination your whole family will adore. Best of all, no rolling or tedious assembly—just stack, cook, and enjoy!
Enchiladas are a Tex-Mex staple with roots in Mexican cuisine. Traditionally, enchiladas were rolled tortillas filled with simple ingredients like beans, meat, or cheese, topped with a chile-based sauce. Over time, variations like this layered enchilada casserole emerged, offering a quicker, more family-friendly approach to this beloved dish. With the popularity of slow cooker recipes, it’s no wonder this version has become a favorite in kitchens everywhere.

Equipment List
- Large Skillet: Perfect for evenly browning the beef[l;;0kl5tflahsh.
- Slow Cooker: The star of the show! It ensures tender, layered perfection.
- Medium Bowl: Ideal for mixing the cheese and soup mixture.
- Nonstick Cooking Spray: Prevents sticking and makes cleanup a breeze.
Ingredients You’ll Need for This Recipe
- Ground Beef: Choose lean for less grease. Substitute ground turkey for a lighter version.
- Corn Tortillas: Soft and pliable, they hold up beautifully during slow cooking.
- Mild Enchilada Sauce: Adds bold, tangy flavor without overwhelming heat.
- Rotel Tomatoes: A zesty addition with green chilies for a little kick.
- Cream of Mushroom Soup: Adds creaminess and depth. Swap with cream of chicken if needed.
- Shredded Cheese: Use a Mexican cheese blend for the ultimate gooey finish.
- Fresh Cilantro: A bright, herby garnish that complements the dish.

How to Make Easy Slow Cooker Layered Beef Enchiladas
Step 1: Prepare the Beef Mixture
- In a large skillet over medium-high heat, crumble and brown the ground beef.
- Stir in enchilada sauce, water, and taco seasoning. Reduce to low and simmer for 5 minutes.






Step 2: Mix the Cheese and Soup
- In a medium bowl, combine Rotel tomatoes and Cream Soup.
- Stir in the cheese, reserving 2 cups for later layering.





Step 3: Layer in the Slow Cooker
- Spray the inside of the slow cooker with nonstick spray.
- Cover the bottom of the slow cooker with a layer of tortillas.
- Spread a portion of the beef mixture, then add a layer of the soup mixture. Sprinkle a bit of the reserved cheese.
- Repeat these layers, finishing with tortillas and the remaining cheese.






Step 4: Cook to Perfection
Cover and cook on high for 2 hours or low for 3–4 hours.

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Chef Secrets & Tips
- Layer Evenly: Thin, even layers ensure each bite is packed with flavor.
- Toast the Tortillas: Lightly toasting tortillas can enhance their flavor and prevent them from becoming too mushy.
- Add a Smoky Kick: Sprinkle a dash of chili powder or smoked paprika into the beef for extra depth.
- Cheese Choices: Combine Monterey Jack and sharp cheddar for a richer taste.
Serving Suggestions
Pair these enchiladas with Mexican rice or my Charro Beans for a complete meal. For drinks, try a refreshing Cucumber Watermelon Mojito or my Creamy Coconut Mojito. Finish with my Pina Colada Cake for a truly indulgent experience.
Commonly Asked Questions
Can I use ground turkey instead of beef?
Absolutely! Ground turkey is a leaner option that works beautifully with this recipe.
What can I use instead of Cream of Mushroom Soup?
Cream of chicken is a great substitute.
Can I make this in an Instant Pot?
Yes! Use the slow-cooker function or cook under high pressure for 20 minutes, followed by a quick release.
Storage & Reheating Tips
- Storing: Transfer leftovers to an airtight container and refrigerate for up to 3 days.
- Reheating: Warm individual portions in the microwave or bake at 350°F until heated through.
- Freezing: Freeze assembled, uncooked layers in a freezer-safe container. Thaw overnight and cook as directed.
With its hearty layers of tender beef, red enchilada sauce, and gooey cheese, this dish is a must-try for any fan of Tex-Mex cuisine. It’s comfort food done right—easy, flavorful, and sure to please everyone around the table!
More Tex-Mex Recipes
If you’re craving more Tex-Mex goodness, there’s no shortage of flavorful recipes to explore!

Homemade Tortilla Chips
Golden and crispy, these homemade tortilla chips are the perfect partner for your favorite dips, from fresh salsa to creamy guacamole or gooey queso. Serve them warm for an irresistible treat.

White Chicken Enchiladas with Creamy Salsa Verde
A creamy and tangy twist on a Tex-Mex classic, these enchiladas are filled with tender chicken, wrapped in tortillas, and smothered in a flavorful salsa verde sauce.

Shredded Beef Tacos with Avocado and Lime
Juicy, slow-cooked shredded beef takes center stage in these tacos, topped with fresh avocado slices and a squeeze of lime for a bright and zesty finish.

Classic Crunchy Ground Beef Tacos
This timeless favorite features seasoned ground beef in crisp taco shells, topped with lettuce, cheese, and salsa for a satisfying, crowd-pleasing meal.

King Ranch Chicken Casserole
Layers of tender chicken, tortillas, cheese, and peppers come together in this hearty, cheesy casserole that’s perfect for feeding the whole family.

Sizzling Beef Fajitas
Loaded with marinated beef, vibrant bell peppers, and onions, these fajitas bring the sizzle and bold flavors of a Tex-Mex restaurant straight to your table.

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Slow Cooker Layered Beef Enchiladas
Ingredients
- 2 pounds ground beef
- 20 (6-inch) corn tortillas quartered
- 1 10-ounce can Old El Paso mild enchilada sauce
- ⅓ cup water
- 1 (1-oz) pkg taco seasoning mix
- 1 10-ounce can ROTEL Original Diced Tomatoes and Green Chilies
- 2 (14.8-oz) cans Campbells Cream of Mushroom Soup
- ½ teaspoon kosher salt
- ¼ teaspoon ground black pepper
- 4 cups Mexican cheese blend shredded
- 1 avocado halved, seeded, peeled and diced, for serving
- 2 tablespoons fresh cilantro leaves chopped, for serving
Instructions
Preparing the Beef Mixture
- Crumble ground beef into a large skillet over medium-high heat.
- Cook and stir until the beef is evenly browned.
- Add enchilada sauce, water, and taco seasoning.
- Reduce heat to low and simmer the mixture for 5 minutes.
Preparing the Cheese and Soup Mixture
- In a medium bowl, combine Rotel tomatoes and Poblano Pepper Cream Soup.
- Reserve 2 cups of shredded cheese for layering later.
- Stir the remaining cheese into the soup mixture until well combined.
Preparing the Slow Cooker
- Spray the inside of the slow cooker with cooking spray to prevent sticking.
Layering the Ingredients
- Place a layer of tortillas to cover the bottom of the slow cooker.
- Add a layer of the ground beef mixture on top of the tortillas.
- Spread a layer of the soup and cheese mixture over the beef.
- Sprinkle a thin layer of the reserved cheese on top.
- Repeat the layering process with the remaining ingredients, finishing with a final layer of tortillas and topping it with the remaining reserved cheese.
Cooking the Dish
- Cover the slow cooker with its lid.
- Cook on High for 2 hours, or on Low for 3 to 4 hours.
Nutrition
*Nutrition information is automatically calculated based on ingredient data and should be considered an estimate. When multiple ingredient options are provided, the first listed is used for calculation. Optional ingredients and garnishes are not included in the nutrition analysis.
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